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1565828-01-4

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1565828-01-4 Structure

1565828-01-4 Structure

Identification	Back Directory
[Name] BRD8518
[CAS] 1565828-01-4
[Synonyms] BRD8518
[Molecular Formula] C33H32F3N3O5
[MOL File] 1565828-01-4.mol
[Molecular Weight] 607.62

Chemical Properties	Back Directory
[Boiling point ] 742.755±60.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.395±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka] 11.760±0.40(predicted)

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[Uses] BRD8518 is a PCSK9 inhibitor (EC50=0.23 μM). BRD8518 lowers blood lipids by upregulating LDLR expression and stimulating LDL uptake. BRD8518 can be used in the study of cardiovascular diseases[1].
[References] [1] Xuhui Bao, et al. "Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside." Signal Transduction and Targeted Therapy 9.1 (2024): 13. DOI:10.1038/s41392-023-01690-3

1565828-01-4 suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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