ChemicalBook--->CAS DataBase List--->156586-89-9

156586-89-9

156586-89-9 Structure

156586-89-9 Structure
IdentificationBack Directory
[Name]

Edrecolomab
[CAS]

156586-89-9
[Synonyms]

17-1A
Panorex
Edrecolomab
Immunoglobulin G 2A (mouse monoclonal 17-1A gamma-chain anti-human colon canceer tumor-associated antigen), disulfide with mouse monoclonal 17-1A light chain, dimer
Immunoglobulin G2A, anti-(human colon cancer tumor-associated antigen) (mouse monoclonal 17-1A gamma2A-chain), disulfide with mouse monoclonal 17-1A light chain, dimer
[MDL Number]

MFCD09832780
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Monoclonal antibody (antineoplastic adjuvant).
[Brand name]

Panorex (Centocor).
[in vivo]

Edrecolomab (intravenous injection; 30 μg/dose; day 1, 4 and 7 after tumor-cell inoculation) treatment inhibits tumor growth in the HT-29 nude mouse model[1].

Animal Model:Male nu/nu mice injected with HT-29 colon carcinoma cells[1]
Dosage:30 μg/dose
Administration:Intravenous injection; 30 μg/dose; day 1, 4 and 7 after tumor-cell inoculation
Result:Inhibited tumor growth with a number of significant readings (p≤0.05).
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