| Identification | Back Directory | [Name]
ent-Toddalolactone | [CAS]
1570054-19-1 | [Synonyms]
ent-Toddalolactone
(-)-Toddalolactone
6-[(2S)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one
2H-1-Benzopyran-2-one, 6-[(2S)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxy- | [Molecular Formula]
C16H20O6 | [MOL File]
1570054-19-1.mol | [Molecular Weight]
308.33 |
| Hazard Information | Back Directory | [Uses]
ent-Toddalolactone is a natural compound with anti-inflammatory and anticancer activities. Ent-Toddalolactone has shown inhibitory effects on phosphodiesterase-4 (PDE4) in vitro and is a potential drug target for inhibiting asthma and chronic obstructive pulmonary disease. The activity of ent-Toddalolactone is related to its unique chemical structure, and some of its derivatives showed IC50 values below 10 μM in inhibition experiments, showing high biological activity[1]. | [References]
[1] Prenylated coumarins: natural phosphodiesterase-4 inhibitors from Toddalia asiatica |
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