| Identification | Back Directory | [Name]
2-(4-Chlorophenyl)-5-nitrobenziMidazole, 95% | [CAS]
1571-87-5 | [Synonyms]
GABAA receptor agent 1
2-(4-Chlorophenyl)-5-nitrobenziMidazole, 95%
2-(4-Chloro-phenyl)-5-nitro-1H-benzoimidazole
1H-Benzimidazole, 2-(4-chlorophenyl)-6-nitro- | [Molecular Formula]
C13H8ClN3O2 | [MDL Number]
MFCD00616523 | [MOL File]
1571-87-5.mol | [Molecular Weight]
273.67 |
| Chemical Properties | Back Directory | [Melting point ]
296 °C | [Boiling point ]
502.1±56.0 °C(Predicted) | [density ]
1.485±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 83.33 mg/mL (304.49 mM) | [form ]
Solid | [pka]
9.47±0.10(Predicted) | [color ]
Light yellow to green yellow | [CAS DataBase Reference]
1571-87-5 |
| Hazard Information | Back Directory | [Uses]
GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity[1]. | [in vivo]
GABAA receptor agent 1 (30 mg/kg; intraperitoneal) inhibits the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions in swiss albino rats[1]. | [storage]
Store at -20°C | [References]
[1] Jain P, et al. Design, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activity. Arch Pharm Res. 2010 Jul;33(7):971-80. DOI:10.1007/s12272-010-0701-8 |
|
| Company Name: |
Alfa Aesar
|
| Tel: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|