| Identification | Back Directory | [Name]
4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide | [CAS]
1573053-23-2 | [Synonyms]
DDR2-IN-1
DDR2 inhibitor
4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide
2-Pyridinecarboxamide, 4-[4-[[[[[4-chloro-2-[2-(dimethylamino)ethoxy]-5-methylphenyl]amino]carbonyl]amino]methyl]-2-methylphenoxy]-N-methyl- | [Molecular Formula]
C27H32ClN5O4 | [MOL File]
1573053-23-2.mol | [Molecular Weight]
526.03 |
| Chemical Properties | Back Directory | [Boiling point ]
680.7±55.0 °C(Predicted) | [density ]
1.248±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.07±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1]. | [References]
[1] Margarita Wucherer-Plietker, et al. Inhibiteurs de ddr2 pour le traitement de l'arthrose. Patent WO2014032755A2. |
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