| Identification | Back Directory | [Name]
Amyloid β-Protein (3-42) | [CAS]
157884-74-7 | [Synonyms]
Amyloid β-Protein (3-42)
Amyloid β-Protein (3-42)
Amyloid β-Protein (3-42) ammonium salt
Amyloidβ-Protein(3-42)ammoniumsalt/Aβ(3-42) |
| Chemical Properties | Back Directory | [form ]
Solid | [color ]
White to off-white | [Sequence]
H-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
| Hazard Information | Back Directory | [Uses]
Amyloid β-Protein (3-42) is the precursor of Pyr peptide. Pyroglutamate-modified Aβ (pEAβ) (3-42) is the core of the amyloid template block in Alzheimer's disease. pEAβ(3-42) accelerated the aggregation of Aβ(1-42), while Aβ(1-42) significantly slowed the primary and secondary nucleation of pEAβ(3-42)[1]. |
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