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157946-92-4

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157946-92-4 Structure

157946-92-4 Structure
IdentificationBack Directory
[Name]

2'-Deoxy-8-methylthio-guanosine
[CAS]

157946-92-4
[Synonyms]

8-methylthio-2'-deoxyguanosine
2'-Deoxy-8-methylthio-guanosine
Guanosine, 2'-deoxy-8-(methylthio)- (9CI)
[Molecular Formula]

C11H15N5O4S
[MDL Number]

MFCD31537264
[MOL File]

157946-92-4.mol
[Molecular Weight]

313.33
Hazard InformationBack Directory
[Uses]

2'-Deoxy-8-methylthioguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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