| Identification | Back Directory | [Name]
2'-Deoxy-8-methylthio-guanosine | [CAS]
157946-92-4 | [Synonyms]
8-methylthio-2'-deoxyguanosine
2'-Deoxy-8-methylthio-guanosine
Guanosine, 2'-deoxy-8-(methylthio)- (9CI) | [Molecular Formula]
C11H15N5O4S | [MDL Number]
MFCD31537264 | [MOL File]
157946-92-4.mol | [Molecular Weight]
313.33 |
| Hazard Information | Back Directory | [Uses]
2'-Deoxy-8-methylthioguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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