| Identification | Back Directory | [Name]
IFN-γ Antagonist, (Tyr121,Cys(Acm)122)-IFN-γ Receptor (120-141) (human) | [CAS]
158040-83-6 | [Synonyms]
IFN-γ Antagonist, (Tyr121,Cys(Acm)122)-IFN-γ Receptor (120-141) (human)
L-Isoleucine,L-alanyl-L-tyrosyl-S-[(acetylamino)methyl]-L-cysteinyl-L-arginyl-L-α-aspartylglycyl-L-lysyl-L-isoleucylglycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-glutaminyl- | [Molecular Formula]
C115H194N34O34S | [MOL File]
158040-83-6.mol | [Molecular Weight]
2629.04 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white | [Sequence]
Ala-Tyr-{Cys(Acm)}-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-{α-Asp}-Ile-Arg-Lys-{α-Glu}-{α-Glu}-Lys-Gln-Ile |
| Hazard Information | Back Directory | [Uses]
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC50 value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation[1]. | [References]
[1] Seelig GF, et al. Development of a receptor peptide antagonist to human gamma-interferon and characterization of its ligand-bound conformation using transferred nuclear Overhauser effect spectroscopy. J Biol Chem. 1995 Apr 21;270(16):9241-9. DOI:10.1074/jbc.270.16.9241 |
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https://www.weikeqi-biotech.com/ |
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