| Identification | Back Directory | [Name]
Methiocarb-d3 | [CAS]
1581694-94-1 | [Synonyms]
Methiocarb-d3
D3-Methiocarb
[2H3]-Methiocarb
Mercaptodimethur-d3
Methiocarb-(N-methyl-d3)
YFBPRJGDJKVWAH-HPRDVNIFSA-N
3,5-Dimethyl-4-(methylthio)phenyl N-methyl-d3-carbamate
(3,5-dimethyl-4-methylsulfanylphenyl) N-(trideuteriomethyl)carbamate | [Molecular Formula]
C11H15NO2S | [MDL Number]
MFCD22200847 | [MOL File]
1581694-94-1.mol | [Molecular Weight]
225.31 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 10 mg/ml | [form ]
neat |
| Hazard Information | Back Directory | [Description]
Methiocarb-d3 is intended for use as an internal standard for the quantification of methiocarb by GC- or LC-MS. Methiocarb is a carbamate pesticide with insecticidal, molluscicidal, acaricidal, and bird repellant properties. It inhibits acetylcholinesterase (AChE) activity and is toxic to the western flower thrip (F. occidentalis; IC50 = 2.1 μM; LC50 = 3.26 ppm). Methiocarb is also toxic to the land snail M. obstructa (LD50 = 27.4 μg/snail) and the citrus mite A. pelekassi, inducing 94% mortality when used at a concentration of 0.5 ppm. It reduces the seasonal percentages of cotton bolls infested with pink bollworm (P. gossypiella) to 4%, compared with 65% infestation in untreated controls, when applied to cotton fields at a concentration of 1.86 lb/acre. Methiocarb reduces damage to grapes by song birds when applied to vineyards at a concentration of 2.5 lbs AI per 100 gal water per acre. It is an estrogen receptor α (ERα) and ERβ agonist (EC20s = 19.87 and 20.24 μM, respectively) and an androgen receptor antagonist (IC50 = 13.89 μM) in cell-based reporter assays. It is toxic to juvenile rainbow trout (O. mykiss) and guppies (P. reticulata) with LC50 values of 0.8 and 1.48 mg/L, respectively, at 48 hours of exposure. Formulations containing methiocarb have been used in the agricultural control of pests. | [Uses]
Isotope labelled Methiocarb acts as a pesticide which is used in the protection of crops from insects and fungus. | [storage]
Store at -20°C | [References]
[1] JENSEN S E. Acetylcholinesterase Activity Associated with Methiocarb Resistance in a Strain of Western Flower Thrips,Frankliniella occidentalis(Pergande)[J]. Pesticide Biochemistry and Physiology, 1998, 61 3: Pages 191-200. DOI: 10.1006/pest.1998.2359
[2] H. HUSSEIN. Molluscicidal activity of Pergularia tomentosa (L.), methomyl and methiocarb, against land snails[J]. International Journal of Pest Management, 1999, 45 1: 211-213. DOI: 10.1080/096708799227815
[3] P. NORMAN C C D K Reed. Pesticides Screened Against Two Rust Mites of Citrus[J]. Journal of Economic Entomology, 1967, 63 1: 1409-1412. DOI: 10.1093/jee/63.5.1409
[4] SATOKO TANGE . In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities[J]. Environmental toxicology and pharmacology, 2016, 41: Pages 289-297. DOI: 10.1016/j.etap.2015.08.014
[5] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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