| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: soluble (Aqueous stock solution is stable for 1 month at 2-8°C and for several months at -20°C.) | [form ]
powder | [color ]
White to off-white | [Water Solubility ]
Soluble in water | [Sequence]
Glu-Asp-Asn-Cys-Ile-Ala-Glu-Asp-Tyr-Gly-Lys-Cys-Thr-Trp-Gly-Gly-Thr-Lys-Cys-Cys-Arg-Gly-Arg-Pro-Cys-Arg-Cys-Ser-Met-Ile-Gly-Thr-Asn-Cys-Glu-Cys-Thr-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Ser-Phe-Ala (Disulfide bridge:Cys4-Cys20,Cys12-Cys25,Cys19-Cys36,Cys27-Cys34) |
| Hazard Information | Back Directory | [Uses]
omega-Agatoxin TK is a selective blocker of the P-type Ca2+??channel. | [Biochem/physiol Actions]
Toxin found in the venom of the funnel web spider, Agelenopsis aptera. Potent, selective P-type and Q-type calcium-channel blocker, without effect on L-type, N-type, or T-type calcium channels. Used to differentiate the types of calcium channel active during various physiological processes | [IC 50]
P/Q-type calcium?channel | [storage]
-20°C (desiccate) |
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Energy Chemical
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