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15854-12-3

15854-12-3 Structure

15854-12-3 Structure
IdentificationBack Directory
[Name]

2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
[CAS]

15854-12-3
[Synonyms]

aPKC-IN-1
Ethyl 2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylate
2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylic acid ethyl ester
3-Thiophenecarboxylic acid, 2-amino-4-(3,4-dimethoxyphenyl)-, ethyl ester
[Molecular Formula]

C15H17NO4S
[MDL Number]

MFCD00499458
[MOL File]

15854-12-3.mol
[Molecular Weight]

307.36
Chemical PropertiesBack Directory
[Boiling point ]

437.3±45.0 °C(Predicted)
[density ]

1.234±0.06 g/cm3(Predicted)
[form ]

solid
[pka]

-0.29±0.10(Predicted)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-41
[Safety Statements ]

26-39
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

aPKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1].
[References]

[1] Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23(10):3034-8. DOI:10.1016/j.bmcl.2013.03.019
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