| Identification | Back Directory | [Name]
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine | [CAS]
158665-47-5 | [Synonyms]
2'-Amino-2'-deoxy-5'-O-DMT-5-methyluridine
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine
Uridine, 2'-?amino-?5'-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2'-?deoxy-?5-?methyl- (9CI) | [Molecular Formula]
C31H33N3O7 | [MOL File]
158665-47-5.mol | [Molecular Weight]
559.62 |
| Hazard Information | Back Directory | [Uses]
2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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