| Identification | Back Directory | [Name]
FAM49B (190-198) mouse | [CAS]
1588388-60-6 | [Synonyms]
FAM49B (190-198) mouse
L-Leucine, L-phenylalanyl-L-tyrosyl-L-alanyl-L-α-glutamyl-L-alanyl-L-threonyl-L-prolyl-L-methionyl- | [Molecular Formula]
C49H71N9O14S | [MOL File]
1588388-60-6.mol | [Molecular Weight]
1042.21 |
| Chemical Properties | Back Directory | [Boiling point ]
1456.1±65.0 °C(predicted) | [density ]
1.313±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
3.37±0.10(predicted) | [color ]
White to off-white | [Sequence]
Phe-Tyr-Ala-Glu-Ala-Thr-Pro-Met-Leu |
| Hazard Information | Back Directory | [Uses]
FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission. FAM49B regulates mitochondrial function and integrity and tumor progression. FAM49B is also a negative regulator in T cell activation, it acts by repressing GTPase Rac activity and modulating cytoskeleton reorganization[1]. | [References]
[1] Chattaragada MS, et al. FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis. Oncogene. 2018 Feb 8;37(6):697-709. DOI:10.1038/onc.2017.358 |
|
|