| Hazard Information | Back Directory | [Description]
L 163255 is a growth hormone secretagogue (GHS). | [Uses]
L-163255 free base is an orally active spiropiperidine GH secretagogue. L-163255 (free base) can also increase plasma IGF-I level[1]. | [in vivo]
L-163255 (3 mg/kg, orally, rats) is effective in inducing GH release[2]. | [References]
[1] C H Chang, et al. Growth hormone (GH) and insulin-like growth factor I responses after treatments with an orally active GH secretagogue L-163,255 in swine. Endocrinology. 1996 Nov;137(11):4851-6. DOI:10.1210/endo.137.11.8895356 [2] Anargyros N Moulas, et al. Effect of the GH secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat. Eur J Endocrinol. 2002 Jul;147(1):143-8. DOI:10.1530/eje.0.1470143 |
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