| Identification | Back Directory | [Name]
Wikstrol A | [CAS]
159736-35-3 | [Synonyms]
Wikstrol A
[3,8'-Bi-4H-1-benzopyran]-4-one, 2',3'-dihydro-3',5,5',7,7'-pentahydroxy-2,2'-bis(4-hydroxyphenyl)-, (2'R,3S,3'S)-
5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-8-yl]chromen-4-one | [Molecular Formula]
C30H22O10 | [MOL File]
159736-35-3.mol | [Molecular Weight]
542.49 |
| Hazard Information | Back Directory | [Uses]
Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 μM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 μM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 μM[1]. | [IC 50]
HIV-1: 67.8 (IC50) | [References]
[1] Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7. DOI:10.1055/s-2000-8601 |
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