| Identification | Back Directory | [Name]
Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl] - | [CAS]
1599440-25-1 | [Synonyms]
Liner
EX-A4328
Schembl17003584
MC-GGFG-Glycolic acid
MC-Gly-Gly-Phe-Gly-Dxd
Mc-Gly-Gly-Phe-2-((2-aminoacetamido)methoxy)acetic acid
(S)-10-benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosanoic acid
(S)-10-benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosan-1-oic acid
Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl] - | [Molecular Formula]
C28H36N6O10 | [MDL Number]
MFCD34471140 | [MOL File]
1599440-25-1.mol | [Molecular Weight]
616.62 |
| Chemical Properties | Back Directory | [Boiling point ]
1137.9±65.0 °C(Predicted) | [density ]
1.341±0.06 g/cm3(Predicted) | [solubility ]
DMSO : 120 mg/mL (194.61 mM; Need ultrasonic) | [form ]
Solid | [pka]
3.20±0.10(Predicted) | [color ]
White to off-white | [InChIKey]
SODPQQOBNODMSG-FQEVSTJZSA-N | [SMILES]
[C@@H](NC(=O)CNC(=O)CNC(=O)CCCCCN1C(C=CC1=O)=O)(C(=O)NCC(=O)NCOCC(=O)O)CC1C=CC=CC=1 |
| Hazard Information | Back Directory | [Description]
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| [Uses]
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [References]
[1] Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1. |
|
|