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160040-04-0

160040-04-0 Structure

160040-04-0 Structure
IdentificationBack Directory
[Name]

HPV16-E711-20 epitope
[CAS]

160040-04-0
[Synonyms]

HPV16-E711-20 epitope
[Molecular Formula]

C53H83N11O19S
[MDL Number]

MFCD32174318
[MOL File]

160040-04-0.mol
[Molecular Weight]

1210.37
Chemical PropertiesBack Directory
[Boiling point ]

1639.2±65.0 °C(Predicted)
[density ]

1.348±0.06 g/cm3(Predicted)
[pka]

3.20±0.10(Predicted)
[Sequence]

Tyr-Met-Leu-Asp-Leu-Gln-Pro-Glu-Thr-Thr
Hazard InformationBack Directory
[Uses]

HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine[1].
[References]

[1] Ding Z, et al. Cytolytic activity of the human papillomavirus type 16 E711-20 epitope-specific cytotoxic T lymphocyte is enhanced by heat shock protein 110 in HLA-A*0201 transgenic mice. Clin Vaccine Immunol. 2013 Jul;20(7):1027-33. DOI:10.1128/CVI.00721-12
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