| Identification | Back Directory | [Name]
Benzamide, 2-[[3-[1-(2-cyclopentylethyl)-1H-1,2,3-triazol-4-yl]phenyl]amino]- | [CAS]
1602731-56-5 | [Synonyms]
A1B11
A-1-B-11
A 1 B 11
Benzamide, 2-[[3-[1-(2-cyclopentylethyl)-1H-1,2,3-triazol-4-yl]phenyl]amino]- | [Molecular Formula]
C22H25N5O | [MOL File]
1602731-56-5.mol | [Molecular Weight]
375.47 |
| Hazard Information | Back Directory | [Description]
A1B11 is a SIRT2-selective inhibitor. | [Uses]
A1B11 is a selective SIRT inhibitor (SIRT2:IC50=5.3 μM) that can be used in the study of neurodegenerative diseases[1]. | [IC 50]
SIRT2: 5.3 μM (IC50) | [References]
[1] Tatum P R, et al. Identification of novel SIRT2-selective inhibitors using a click chemistry approach[J]. Bioorganic & medicinal chemistry letters, 2014, 24(8): 1871-1874. DOI:10.1016/j.bmcl.2014.03.026 |
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