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160295-81-8

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160295-81-8 Structure

160295-81-8 Structure
IdentificationBack Directory
[Name]

H-PHE-LEU-TRP-GLY-PRO-ARG-ALA-LEU-VAL-OH
[CAS]

160295-81-8
[Synonyms]

FLWGPRALV
MAGE-3 (271-279)
H2N-FLWGPRALV-OH
MAGE-3 HUMAN (271-279)
MAGE-3 ANTIGEN (271-279) (HUMAN)
PHE-LEU-TRP-GLY-PRO-ARG-ALA-LEU-VAL
H-PHE-LEU-TRP-GLY-PRO-ARG-ALA-LEU-VAL-OH
PHE-LEU-TRP-GLY-PRO-ARG-ALA-LEU-VAL: FLWGPRALV
MELANOMA-ASSOCIATED ANTIGEN 3 (271-279) (HUMAN)
MAGE-3 Antigen (271-279) (huMan) MelanoMa-Associated Antigen 3 (271-279) (huMan)
L-Phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-L-arginyl-L-alanyl-L-leucyl-L-valine
L-Valine, L-phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-L-arginyl-L-alanyl-L-leucyl-
[Molecular Formula]

C53H79N13O10
[MDL Number]

MFCD00943339
[MOL File]

160295-81-8.mol
[Molecular Weight]

1058.28
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

3.37±0.10(Predicted)
[Sequence]

Phe-Leu-Trp-Gly-Pro-Arg-Ala-Leu-Val
Hazard InformationBack Directory
[Uses]

MAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta[1].
[References]

[1] J Herman, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83. DOI:10.1007/BF02199806
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