| Identification | Back Directory | [Name]
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib | [CAS]
1603814-04-5 | [Synonyms]
Desfluoro Gefitinib
Gefitinib Impurity 16
Gefitinib Impurity HCl
Gefitinib EP impurity B
Gefitinib related substance B
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Gefitinib Impurity HCl (3-Deschloro-4-Desfluoro-4-Chloro-3-Fluoro Gefitinib HCl)
N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
4-Quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]- | [Molecular Formula]
C22H24ClFN4O3 | [MDL Number]
MFCD29039079 | [MOL File]
1603814-04-5.mol | [Molecular Weight]
446.9 |
| Chemical Properties | Back Directory | [Melting point ]
180-183oC | [Boiling point ]
585.0±50.0 °C(Predicted) | [density ]
1.322±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
7.00±0.10(Predicted) | [color ]
Off-White to Light Brown | [Major Application]
pharmaceutical |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Chronic 2
Carc. 2
Eye Dam. 1
Repr. 1B
Skin Irrit. 2
STOT RE 2 Oral |
| Hazard Information | Back Directory | [Uses]
3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR). |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Roark Standards
|
| Tel: |
0755-83552066 15986688328 |
| Website: |
roarkstandards.com |
| Company Name: |
Cool Pharm, Ltd
|
| Tel: |
021-58581007 18019463053 |
| Website: |
http://www.coolpharm.com.cn |
| Company Name: |
TOSUN PHARM
|
| Tel: |
61855200 13326451905 |
| Website: |
www.toref.cn/ |
|