| Identification | Back Directory | [Name]
GP2 | [CAS]
160790-21-6 | [Synonyms]
GP2
IISAVVGIL
HER-2/NEU (654-662)
HER2/NEU (654-662) GP2
ILE-ILE-SER-ALA-VAL-VAL-GLY-ILE-LEU
H-ILE-ILE-SER-ALA-VAL-VAL-GLY-ILE-LEU-OH | [Molecular Formula]
C42H77N9O11 | [MDL Number]
MFCD00950499 | [MOL File]
160790-21-6.mol | [Molecular Weight]
884.11 |
| Chemical Properties | Back Directory | [Boiling point ]
1209.5±65.0 °C(Predicted) | [density ]
1.147±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.41±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Ile-Ile-Ser-Ala-Val-Val-Gly-Ile-Leu |
| Hazard Information | Back Directory | [Uses]
HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2]. | [References]
[1] Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306. DOI:10.1371/journal.pone.0050306
[2] Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4. DOI:10.1002/ijc.1508 |
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| Company Name: |
Ontores Biotech
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0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
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