| Identification | Back Directory | [Name]
1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) | [CAS]
1609461-57-5 | [Synonyms]
1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) | [Molecular Formula]
C19H14F3N5O2.ClH | [MOL File]
1609461-57-5.mol | [Molecular Weight]
437.8 |
| Hazard Information | Back Directory | [Uses]
HV1-IN-1 hydrochloride is an inhibitor of the human voltage-gated proton channel (hHV1). HV1-IN-1 hydrochloride works by binding to the VSD of the HV1 channel. The VSD is a component of the HV1 channel that is responsible for detecting changes in membrane potential and triggering the opening of the channel. HV1-IN-1 hydrochloride can be used in the study of cancer, neuroinflammation and immune response[1]. | [References]
[1] Piga M, et al. Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening[J]. Journal of Chemical Information and Modeling, 2024. DOI:10.1021/acs.jcim.4c00240 |
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