| Hazard Information | Back Directory | [Description]
APA-APA-MPO is an inhibitor of PCAF bromodomaiTat-AcK50 association. | [Uses]
APA-APA-MPO dihydrochloride is an inhibitor of PCAF bromodomain/Tat-AcK50 interaction with reduced cytotoxic activity. APA-APA-MPO dihydrochloride can effectively inhibit the binding of PCAF to Tat-AcK50, showing its potential in HIV/AIDS inhibitory strategies. APA-APA-MPO dihydrochloride can be used in studies that hinder HIV replication[1]. | [References]
[1] Fluorescence polarization for the evaluation of small-molecule inhibitors of PCAF BRD/Tat-AcK50 association DOI:10.1002/cmdc.201300499 |
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