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1612191-89-5

1612191-89-5 Structure

1612191-89-5 Structure
IdentificationBack Directory
[Name]

6-(Furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside
[CAS]

1612191-89-5
[Synonyms]

6-(Furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside
6-(Furan-2-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside
9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furanyl)-
(2R,3S,4S,5R)-4-Fluoro-2-(6-(furan-2-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol
[Molecular Formula]

C14H13FN4O4
[MOL File]

1612191-89-5.mol
[Molecular Weight]

320.28
Chemical PropertiesBack Directory
[Boiling point ]

616.6±65.0 °C(Predicted)
[density ]

1.78±0.1 g/cm3(Predicted)
[pka]

12.45±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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