| Identification | Back Directory | [Name]
2-Chloro-6-(furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside | [CAS]
1612192-00-3 | [Synonyms]
2-Chloro-6-(furan-2-yl)purine-β-D-(3’-deoxy-3’-fluoro)riboside
2-Chloro-6-(furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside
9H-?Purine, 2-?chloro-?9-?(3-?deoxy-?3-?fluoro-?β-?D-?ribofuranosyl)?-?6-?(2-?furanyl)?- | [Molecular Formula]
C14H12ClFN4O4 | [MDL Number]
MFCD29915415 | [MOL File]
1612192-00-3.mol | [Molecular Weight]
354.72 |
| Hazard Information | Back Directory | [Uses]
2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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