ChemicalBook--->CAS DataBase List--->1612192-04-7

1612192-04-7

1612192-04-7 Structure

1612192-04-7 Structure
IdentificationBack Directory
[Name]

(2R,3S,4S,5R)-2-(2-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
[CAS]

1612192-04-7
[Synonyms]

9H-Purin-2-amine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-
2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine
(2R,3S,4S,5R)-2-(2-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
[Molecular Formula]

C10H12FN5O3
[MDL Number]

MFCD25542496
[MOL File]

1612192-04-7.mol
[Molecular Weight]

269.232
Chemical PropertiesBack Directory
[Boiling point ]

662.9±65.0 °C(Predicted)
[density ]

2.01±0.1 g/cm3(Predicted)
[pka]

12.45±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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