| Identification | Back Directory | [Name]
A85380 | [CAS]
161416-98-4 | [Synonyms]
A85380
(S)-3-(2-Azetidinylmethoxy)pyridine
Pyridine, 3-(2-azetidinylMethoxy)-, (S)- | [Molecular Formula]
C9H12N2O | [MDL Number]
MFCD00672647 | [MOL File]
161416-98-4.mol | [Molecular Weight]
164.2 |
| Chemical Properties | Back Directory | [Boiling point ]
283.7±10.0 °C(Predicted) | [density ]
1.096±0.06 g/cm3(Predicted) | [solubility ]
H2O: 10 mg/mL | [form ]
solid | [pka]
10.15±0.40(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Uses]
A 85380 is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. A 85380 exhibits selectivity for the α4β2 nAChR subtypes. A 85380 has a broad-spectrum analgesic profile[1]. | [References]
[1] Sullivan J P, et al. A-85380 [3-(2 (S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand[J]. Neuropharmacology, 1996, 35(6): 725-734. |
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