| Identification | Back Directory | [Name]
PHT-7.3 | [CAS]
1614225-93-2 | [Synonyms]
PHT-7.3
1(2H)-Phthalazinone, 4-(1,3-dioxan-2-ylmethyl)-2-[[4-(4-methylphenyl)-2-thiazolyl]methyl]- | [Molecular Formula]
C24H23N3O3S | [MDL Number]
MFCD32067972 | [MOL File]
1614225-93-2.mol | [Molecular Weight]
433.52 |
| Chemical Properties | Back Directory | [Boiling point ]
629.2±65.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 62.5 mg/mL (144.17 mM) | [form ]
Solid | [pka]
2.00±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, which inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling. |
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