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161615-21-0

161615-21-0 Structure

161615-21-0 Structure
IdentificationBack Directory
[Name]

2'-O-Acetyl-3',5'-di-O-benzoyl-6-azauridine
[CAS]

161615-21-0
[Synonyms]

2'-O-Acetyl-3',5'-di-O-benzoyl-6-azauridine
2'-O-Acetyl-3',5'-bis-O-benzoyl-6-aza-xylouridine
1-(2'-O-Acetyl-3',5'-bis-O-benzoyl-b-D-xylofuranosyl)-6-azauracil
[Molecular Formula]

C24H21N3O9
[MDL Number]

MFCD30570200
[MOL File]

161615-21-0.mol
[Molecular Weight]

495.438
Chemical PropertiesBack Directory
[density ]

1.47±0.1 g/cm3(Predicted)
[pka]

7?+-.0.20(Predicted)
Hazard InformationBack Directory
[Uses]

2’-O-Acetyl-3’,5’-bis-O-benzoyl-6-aza-xylo uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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