ChemicalBook--->CAS DataBase List--->1616967-52-2

1616967-52-2

1616967-52-2 Structure

1616967-52-2 Structure
IdentificationBack Directory
[Name]

CAY10701
[CAS]

1616967-52-2
[Synonyms]

CAY10701
[Molecular Formula]

C24H19N3O2
[MOL File]

1616967-52-2.mol
[Molecular Weight]

381.43
Chemical PropertiesBack Directory
[Boiling point ]

664.2±65.0 °C(Predicted)
[density ]

1.22±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Ethanol: 10 mg/ml,Methanol: 10 mg/ml
[pka]

14.19±0.20(Predicted)
Hazard InformationBack Directory
[Description]

CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
[Uses]

CAY10701 (Compound 20) is a 7-deazahypoxanthine analogue with anticancer activity[1].
[References]

[1] van der Westhuyzen, et al. "Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems." Journal of Medicinal Chemistry (2024). DOI:10.1021/acs.jmedchem.5b01426
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