| Chemical Properties | Back Directory | [Boiling point ]
664.2±65.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Ethanol: 10 mg/ml,Methanol: 10 mg/ml | [pka]
14.19±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). | [Uses]
CAY10701 (Compound 20) is a 7-deazahypoxanthine analogue with anticancer activity[1]. | [References]
[1] van der Westhuyzen, et al. "Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems." Journal of Medicinal Chemistry (2024). DOI:10.1021/acs.jmedchem.5b01426 |
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