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U 89360E is a peptidic inhibitor. | [Uses]
U-89360E is an inhibitor for HIV-1 protease. U-89360E inhibits the protease of HIV-1 wildtype, V82D mutant and V82N mutant with Ki of 20 nM, 560 nM and 2100 nM, respectively[1]. | [References]
[1] Hong L, et al., Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases. Biochemistry. 1996 Aug 20;35(33):10627-33. DOI:10.1021/bi960481s |
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