ChemicalBook--->CAS DataBase List--->161928-86-5

161928-86-5

161928-86-5 Structure

161928-86-5 Structure
IdentificationBack Directory
[Name]

GP (33-41)
[CAS]

161928-86-5
[Synonyms]

GP33 (1-9)
GP (33-41)
LCMV PEPTIDE
H2N-KAVYNFATM-OH
LYS-ALA-VAL-TYR-ASN-PHE-ALA-THR-MET
Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys
LYMPHOCYTIC CHORIOMENINGITIS VIRUS PEPTIDE
[Molecular Formula]

C48H73N11O13S
[MDL Number]

MFCD02181018
[MOL File]

161928-86-5.mol
[Molecular Weight]

1044.22
Chemical PropertiesBack Directory
[Boiling point ]

1490.5±65.0 °C(Predicted)
[density ]

1.310±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

2.94±0.10(Predicted)
[Sequence]

Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys
Hazard InformationBack Directory
[Uses]

GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2Db molecules at the RMA-S (Db Kb) cell surface with a SC50 of 344 nM[1].
[References]

[1] Gairin JE, et al. Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes. J Virol. 1995 Apr;69(4):2297-305. DOI:10.1128/JVI.69.4.2297-2305.1995
[2] Boulter JM, et al. Potent T cell agonism mediated by a very rapid TCR/pMHC interaction. Eur J Immunol. 2007 Mar;37(3):798-806. DOI:10.1002/eji.200636743
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