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162050-43-3

162050-43-3 Structure

162050-43-3 Structure
IdentificationBack Directory
[Name]

DL-3-(3'-Hydroxy)Butylphthalide
[CAS]

162050-43-3
[Synonyms]

Butylphthalide Impurity 38
DL-3-(3'-Hydroxy)Butylphthalide
1(3H)-Isobenzofuranone, 3-(3-hydroxybutyl)-
Butylphthalide Impurity 38(3-Butylphthalide Impurity 52)
[Molecular Formula]

C12H14O3
[MDL Number]

MFCD14706132
[MOL File]

162050-43-3.mol
[Molecular Weight]

206.24
Chemical PropertiesBack Directory
[Boiling point ]

369.4±35.0 °C(Predicted)
[density ]

1.181±0.06 g/cm3(Predicted)
[pka]

15.05±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

10-OH-NBP-d4 is deuterium labeled 10-OH-NBP. 10-OH-NBP is a Butylphthalide (3-n-Butylphthalide; NBP; HY-B0647) hydroxylated metabolite and can penetrates the blood-brain barrier (BBB). Butylphthalide exerts neuroprotective effects and has potential for cerebral ischemia research[1].
[References]

[1] Xing-xing Diao, et al. Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier. Acta Pharmacol Sin. 2015 Dec;36(12):1520-7. DOI:10.1038/aps.2015.64
Spectrum DetailBack Directory
[Spectrum Detail]

DL-3-(3'-Hydroxy)Butylphthalide(162050-43-3)1HNMR
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