| Chemical Properties | Back Directory | [Boiling point ]
585.625±33.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.074±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Oil | [pka]
14.475±0.70(predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
UCM-13207 (compound 21) is a selective ICMT inhibitor that ameliorates basic progeria-like features. UCM-13207 can improve the survival rate of LmnaG609G/G609G mice in the mouse premature aging model[1]. | [References]
[1] Marcos-Ramiro B et al. Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome[J]. ACS Central Science, 2021, 7(8): 1300-1310. |
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