| Hazard Information | Back Directory | [Description]
CGA-JK3 is a novel inhibitor of IkappaB kinase in innate immune process. | [Uses]
CGA-JK3 is CGA-JK3 is an ATP-competitive inhibitor of IKKβ-catalyzed kinase activity. CGA-JK3 inhibits IκBα phosphorylation in LPS (HY-D1056) - induced RAW 264.7 cells[1]. | [References]
[1] Choi JH, et al. Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process. Sci Rep. 2017;7:41180. Published 2017 Feb 1. DOI:10.1038/srep41180 |
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