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1628574-50-4

1628574-50-4 Structure

1628574-50-4 Structure
IdentificationBack Directory
[Name]

c-Fms-IN-9
[CAS]

1628574-50-4
[Synonyms]

c-Fms-IN-9
cFmsIN9,c Fms IN 9
[Molecular Formula]

C21H23N7O2
[MDL Number]

MFCD32067991
[MOL File]

1628574-50-4.mol
[Molecular Weight]

405.45
Chemical PropertiesBack Directory
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

8.97±0.20(Predicted)
Hazard InformationBack Directory
[Description]

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1]. c-FMS[1]

c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].

[Uses]

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].
[storage]

Store at -20°C
[References]

[1]. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

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