| Identification | Back Directory | [Name]
K-Ras G12C-IN-2 | [CAS]
1629267-75-9 | [Synonyms]
K-Ras G12C-IN-2
K-Ras G-12C-IN-2,K Ras G12C IN 2,KRas G12CIN2
1-(3-(4-((4-chloro-5-cyclopropyl-2-hydroxyphenyl)glycyl)piperazin-1-yl)azetidin-1-yl)prop-2-en-1-one
1-[3-[4-[2-(4-chloro-5-cyclopropyl-2-hydroxyanilino)acetyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one
2-Propen-1-one, 1-[3-[4-[2-[(4-chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]- | [Molecular Formula]
C21H27ClN4O3 | [MOL File]
1629267-75-9.mol | [Molecular Weight]
418.92 |
| Chemical Properties | Back Directory | [Boiling point ]
675.7±55.0 °C(Predicted) | [density ]
1.393±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: ≥ 22 mg/mL (52.52 mM) | [form ]
Powder | [pka]
9.35±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor. | [IC 50]
KRas G12C | [storage]
Store at -20°C | [References]
[1] Pingda Ren, et al. Covalent inhibitors of kras g12c. WO2014152588A1 |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
|