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1630114-57-6

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1630114-57-6 Structure

1630114-57-6 Structure
IdentificationBack Directory
[Name]

NH2-NODA-GA
[CAS]

1630114-57-6
[Synonyms]

NH2-NODA-GA
1H-1,4,7-Triazonine-1,4,7-triacetic acid, α1-[3-[(2-aminoethyl)amino]-3-oxopropyl]hexahydro-
[Molecular Formula]

C17H31N5O7
[MOL File]

1630114-57-6.mol
[Molecular Weight]

417.46
Chemical PropertiesBack Directory
[Boiling point ]

767.8±60.0 °C(Predicted)
[density ]

1.306±0.06 g/cm3(Predicted)
[pka]

1.55±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

NH2-NODAGA is a NODAGA-type metal chelator that can bind to radionuclides to prepare radionuclide conjugates (RDCs). NH2-NODAGA can react with diethyl squarate in 0.5M phosphate buffer (room temperature, 2 h, pH 7-7.5) to obtain NODAGA.SA. NODAGA.SA can target L-lysine urea-L-glutamate (KuE), which is a key structure of prostate-specific membrane antigen (PSMA). NODAGA.SA.KuE can bind [68]Ga and can be used for PET examination of NMRInu/nu nude mice bearing LNCaP tumors.
[IC 50]

RDC Bifunctional Chelator
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