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163597-24-8

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163597-24-8 Structure

163597-24-8 Structure
IdentificationBack Directory
[Name]

antcin A
[CAS]

163597-24-8
[Synonyms]

antcin A
antcin A，(R,S)-Antcin A
[Molecular Formula]

C29H42O4
[MOL File]

163597-24-8.mol
[Molecular Weight]

454.65
Chemical PropertiesBack Directory
[Boiling point ]

605.0±55.0 °C(Predicted)
[density ]

1.11±0.1 g/cm3(Predicted)
[pka]

4.59±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Antcin A is a potent NLRP3 inhibitor that inhibits the assembly and activation of the NLRP3 inflammasome. Antcin A can inhibit Kupffer cell pyroptosis and has liver protective activity. Antcin A can be used to study inflammation, such as non-alcoholic fatty liver disease[1].
[Definition]

ChEBI: Antcin A is an ergostanoid. It has a role as a metabolite.
[References]

[1] Ruan S, et al. Antcin A alleviates pyroptosis and inflammatory response in Kupffercells of non-alcoholic fatty liver disease by targeting NLRP3. Int Immunopharmacol. 2021 Nov;100:108126. DOI:10.1016/j.intimp.2021.108126
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