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1637297-21-2

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1637297-21-2 Structure

1637297-21-2 Structure
IdentificationBack Directory
[Name]

Azido-PEG20-alcohol
[CAS]

1637297-21-2
[Synonyms]

azido-PEG20-OH
N3-PEG20-alcohol
Azido-PEG20-alcohol
3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-Nonadecaoxanonapentacontan-1-ol,59-azido-
[Molecular Formula]

C40H81N3O20
[MDL Number]

MFCD13184941
[MOL File]

1637297-21-2.mol
[Molecular Weight]

924.09
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P304+P340-P305+P351+P338
[HS Code ]

2942000090
Hazard InformationBack Directory
[Uses]

Azido-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG20-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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