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1638211-04-7

1638211-04-7 Structure

1638211-04-7 Structure
IdentificationBack Directory
[Name]

2-Methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol
[CAS]

1638211-04-7
[Synonyms]

ML303
2-Methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol
[Molecular Formula]

C21H16F3N3O2
[MDL Number]

MFCD28168046
[MOL File]

1638211-04-7.mol
[Molecular Weight]

399.37
Chemical PropertiesBack Directory
[Boiling point ]

483.6±45.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 20mg/mL, clear
[form ]

powder
[pka]

8.01±0.20(Predicted)
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P301+P310
[Hazard Codes ]

T
[Risk Statements ]

25
[Safety Statements ]

45
[RIDADR ]

UN 2811 6.1 / PGIII
Hazard InformationBack Directory
[Biological Activity]

It belongs to the pyrazolopyridine family.''ML303 is a potent inhibitor (IC50 = 155 nM) of the influenza viral protien NS1. NS1 enhances virulence by inhibiting host cell immune responsesincluding the expression of IFN-band regulating synthesissplicing and translation of viral RNA.
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