| Identification | Back Directory | [Name]
TAPI-1 | [CAS]
163847-77-6 | [Synonyms]
TAPI-1
(2R)-TAPI-1
TAPI-1 acetate salt
TNF-ALPHA PROTEASE INHIBITOR-1
HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NHCH2CH2NH2
N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)--alanyl-L-alaninamide
N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE, 2-AMINOETHYL AMIDE
N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL)ALANYL-L-ALANINE 2-AMINOETHYL AMIDE
L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-
N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt | [Molecular Formula]
C26H37N5O5 | [MDL Number]
MFCD02684280 | [MOL File]
163847-77-6.mol | [Molecular Weight]
499.6 |
| Chemical Properties | Back Directory | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
powder | [pka]
9.17±0.20(Predicted) | [color ]
white to beige | [InChIKey]
AWNBSWDIOCXWJW-WTOYTKOKSA-N | [SMILES]
N(O)C(=O)C[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cc2c(cc1)cccc2)C(=O)N[C@@H](C)C(=O)NCCN |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
25 | [Safety Statements ]
45 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3 | [HS Code ]
2928009090 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Uses]
TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor. | [Biochem/physiol Actions]
TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). | [storage]
Store at -20°C |
|
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|