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1638885-65-0

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1638885-65-0 Structure

1638885-65-0 Structure
IdentificationBack Directory
[Name]

Apalutamide D4
[CAS]

1638885-65-0
[Synonyms]

Apalutamide D4
[Molecular Formula]

C21H15F4N5O2S
[MDL Number]

MFCD32874130
[MOL File]

1638885-65-0.mol
[Molecular Weight]

477.44
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Solid
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
[References]

[1] Clegg NJ, et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res. 2012 Mar 15;72(6):1494-503. DOI:10.1158/0008-5472.CAN-11-3948
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