| Identification | Back Directory | [Name]
Axitinib Impurity 27 | [CAS]
1639137-80-6 | [Synonyms]
Axitinib J N-Acetyl Axitinib Axitinib Impurity 27 (E)-2-((1-acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide Benzamide, 2-[[1-acetyl-3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-N-methyl- (E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity) Axitinib Impurity 11/(E)-2-((1-acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide | [Molecular Formula]
C24H20N4O2S | [MOL File]
1639137-80-6.mol | [Molecular Weight]
428.51 |
| Chemical Properties | Back Directory | [Melting point ]
214 - 215°C | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, Inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.42±0.46(Predicted) | [color ]
Light Yellow to Yellow | [InChI]
InChI=1S/C24H20N4O2S/c1-16(29)28-22-15-18(31-23-9-4-3-8-20(23)24(30)25-2)11-12-19(22)21(27-28)13-10-17-7-5-6-14-26-17/h3-15H,1-2H3,(H,25,30)/b13-10+ | [InChIKey]
DPCLTPPDTUVUIL-JLHYYAGUSA-N | [SMILES]
C(NC)(=O)C1=CC=CC=C1SC1=CC2=C(C=C1)C(/C=C/C1=NC=CC=C1)=NN2C(C)=O |
| Hazard Information | Back Directory | [Uses]
N-Acetyl Axitinib is an intermediate used in the synthesis of Axitinib. Axitinib is a tyrosine kinase inhibitor that is also used in cancer therapy. |
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| Company Name: |
TOSUN PHARM
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| Tel: |
61855200 13326451905 |
| Website: |
www.toref.cn/ |
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