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1643326-82-2

1643326-82-2 Structure

1643326-82-2 Structure
IdentificationBack Directory
[Name]

Urea, N-[(1S,1aS,6bS)-1a,6b-dihydro-5-[(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-4-yl)oxy]-1H-cyclopropa[b]benzofuran-1-yl]-N'-(2,4,5-trifluorophenyl)-
[CAS]

1643326-82-2
[Synonyms]

Brimarafenib
BGB-3245(Brimarafenib)
1-[(1S,1aS,6bS)-5-[(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-4-yl)oxy]-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-1-yl]-3-(2,4,5-trifluorophenyl)urea
Urea, N-[(1S,1aS,6bS)-1a,6b-dihydro-5-[(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-4-yl)oxy]-1H-cyclopropa[b]benzofuran-1-yl]-N'-(2,4,5-trifluorophenyl)-
[Molecular Formula]

C24H17F3N4O4
[MOL File]

1643326-82-2.mol
[Molecular Weight]

482.41
Chemical PropertiesBack Directory
[density ]

1.70±0.1 g/cm3(Predicted)
[pka]

11.74±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Brimarafenibum (Brimarafenib) is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor, wtih antineoplastic effect[1].
[References]

[1] Brimarafenibum (Brimarafenib). WHO Drug Information, Vol. 37, No. 4, 2023.
Spectrum DetailBack Directory
[Spectrum Detail]

Urea, N-[(1S,1aS,6bS)-1a,6b-dihydro-5-[(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-4-yl)oxy]-1H-cyclopropa[b]benzofuran-1-yl]-N'-(2,4,5-trifluorophenyl)-(1643326-82-2)1HNMR
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