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1643593-28-5

1643593-28-5 Structure

1643593-28-5 Structure
IdentificationBack Directory
[Name]

2-Propenamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-3-(3,5-dibromo-4-methoxyphenyl)-, (2E)-, 2,2,2-trifluoroacetate (1:3)
[CAS]

1643593-28-5
[Synonyms]

IanthelliformisamineA TFA
Ianthelliformisamine-A TFA
Ianthelliformisamine A TFA
Ianthelliformisamine A TFA salt
2-Propenamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-3-(3,5-dibromo-4-methoxyphenyl)-, (2E)-, 2,2,2-trifluoroacetate (1:3)
[Molecular Formula]

C22H33Br2F3N4O4
[MDL Number]

MFCD30146220
[MOL File]

1643593-28-5.mol
[Molecular Weight]

634.33
Hazard InformationBack Directory
[Description]

Ianthelliformisamine A TFA is an antibiotic enhancer against resistant Gram-negative bacteria.
[Uses]

Ianthelliformisamine A TFA is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine A TFA exhibits bactericidal activity against Staphylococcus aureus with an IC50 value of 3.8 μM (minimum inhibitory concentration = 25 μM). The biological activity of Ianthelliformisamine A TFA is derived from the structural variation of its synthetic derivatives and its coupling reaction with different amino ester derivatives[1].
[References]

[1] Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues DOI:10.1016/j.bmcl.2021.127883
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