| Identification | Back Directory | [Name]
DHODH-IN-9 | [CAS]
1644156-41-1 | [Synonyms]
DHODH-IN-9
hDHODH-IN-7
hDHODH IN 7,hDHODHIN7
hDHODH-IN-7, 10 mM in DMSO
Pyrimidine, 5-cyclopropyl-2-[4-[(2-fluorophenyl)methyl]-5-methyl-3-(1-methylethoxy)-1H-pyrazol-1-yl]- | [Molecular Formula]
C21H23FN4O | [MDL Number]
MFCD32667248 | [MOL File]
1644156-41-1.mol | [Molecular Weight]
366.43 |
| Hazard Information | Back Directory | [Uses]
DHODH-IN-9 (Compound 10k) is an azine-bearing analogue and is a human dihydroorotate dehydrogenase inhibitor. DHODH-IN-9 has antiviral effect with a pMIC50 of 7.4[1]. | [References]
[1] Lucas-Hourani M, et al.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98. DOI:10.1021/acs.jmedchem.5b00606 |
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