| Chemical Properties | Back Directory | [Boiling point ]
611.5±65.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (342.99 mM) | [form ]
Solid | [pka]
12.52±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8[1]. | [storage]
Store at -20°C | [References]
[1] Munier-Lehmann H, et al. Original?2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine?derivatives?as?inhibitors?of?human?dihydroorotate?dehydrogenase?(DHODH). J Med Chem.?2015 Jan 22;58(2):860-77. DOI:10.1021/jm501446r |
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