| Identification | Back Directory | [Name]
BPI-15086 | [CAS]
1644502-33-9 | [Synonyms]
BPI-15086
Benzeneacetamide, 2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)-5-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-4-pyrimidinyl]amino]-N,N-dimethyl-α-oxo- | [Molecular Formula]
C29H33ClN8O4 | [MOL File]
1644502-33-9.mol | [Molecular Weight]
593.08 |
| Hazard Information | Back Directory | [Uses]
BPI-15086 an orally active, potent, irreversible mutant-selective inhibitor of both EGFR and T790M resistance mutations tyrosine kinase. BPI-15086 can be used for the research of non-small-cell lung cancer[1]. | [References]
[1] Wang S, et al. Determination of BPI15086 and its metabolite in human plasma by ultra-high performance liquid chromatography-MS/MS and its application to a pharmacokinetic study. Bioanalysis. 2019 Apr;11(8):773-784. DOI:10.4155/bio-2018-0307 |
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