| Identification | Back Directory | [Name]
L-Valinamide, N4-[3-methyl-N-[(phenylmethoxy)carbonyl]-L-valyl]-4-amino-2,4,5-trideoxy-2-[[(4-methoxyphenyl)methyl]amino]-5-phenyl-L-lyxonoyl-N-[(2-hydroxy-4-methoxyphenyl)methyl]- | [CAS]
164514-54-9 | [Synonyms]
910
SDZ283
SDZ-283
SDZ 283
L-Valinamide, N4-[3-methyl-N-[(phenylmethoxy)carbonyl]-L-valyl]-4-amino-2,4,5-trideoxy-2-[[(4-methoxyphenyl)methyl]amino]-5-phenyl-L-lyxonoyl-N-[(2-hydroxy-4-methoxyphenyl)methyl]- | [Molecular Formula]
C46H59N5O9 | [MOL File]
164514-54-9.mol | [Molecular Weight]
825.99 |
| Hazard Information | Back Directory | [Description]
SDZ 283-910 is a statine-derived inhibitor . | [Uses]
SDZ283-910 is a potent human immunodeficiency virus type-1 (HIV-1) protease inhibitor[1]. | [IC 50]
HIV-1 | [References]
[1] S Ringhofer, et al. X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations. J Mol Biol. 1999 Mar 5;286(4):1147-59. DOI:10.1006/jmbi.1998.2533 |
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